Dr. Hao Xu
Associate Professor
Bio
Mast cells play a critical role in immunity, allergy, autoimmune disease, cardiovascular disorders, and cancer by releasing a wide range of mediators (e.g., histamine, TNF) in a SNARE and Munc18 dependent fashion. These highly regulated exocytic events are coupled intimately to the signaling cascades, which is not well understood at the molecular level.
My research team investigates the catalyti